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April 2016

  The TCRN is a translational cancer research centre program funded by the Cancer Institute NSW Cancer Institute NSW  
bullet Welcome to the TCRN April Nexus
This month marks reaching over 2,000 consents for the HSA Biobank, a significant milestone for the biobank. As a joint initiative between UNSW Australia and the South Eastern Sydney Local Health District, the HSA Biobank houses tumour, blood and saliva samples and clinical data from consenting cancer patients undergoing cancer surgery at participating NSW hospitals.

We feature the most recent and interesting publications by the the TCRN membership, as well as recent TCRN Conference grant recipients Nadia Amorim and Ashleigh Swain from the Cellular and Genetic Medicine Unit at UNSW, who both presented at Lorne Cancer Conference.

We interview TCRN Research Associate Dr Heike Schütze following her return from presenting the TCRN Primary Care project at the International Primary Health Care Reform conference in Brisbane, where she had an opportunity to share the results of the research project that could transform the delivery of cancer follow-up care.

Also this month, there are a number of open abstract submissions for upcoming conferences of interest to clinical and research staff.
Prof Phil Crowe, Surgical Oncology Prince of Wales Hospital Two Thousand Consents and Counting

This month marks the 2000th HSA Biobank Patient Consent Form, reaffirming the bank as one of the most valuable translational research resources in NSW as we hear from Surgical Oncologist Prof Phil Crowe.

Providing unique access to biospecimens and linked de-identified patient health data

TCRN Members Monthly Publications Recent Interesting Articles From TCRN Members

This month's article features recently published studies by TCRN members at UNSW, Lowy Cancer Research Centre and Macquarie University...
Learn more about research published this month by TCRN members

Ashleigh Swain 2 Broadening Research Horizons at the Lorne Cancer Conference

One of Australia’s most high profile cancer conferences provided an opportunity for two TCRN PhD students to present their research findings to an international audience...
Learn more about PhD students Nadia Amorim and Ashleigh Swain who received TCRN Conference and Professional Development Grants

TCRN Primary Care project Getting the Word Out on Cancer Follow-up Care

Presenting the TCRN Primary Care project at the International Primary Health Care Reform conference gave Dr Heike Schütze an opportunity to share the results of a research project that could transform the delivery of cancer follow-up care...
Continuing care to cancer survivors...

CCY15 Lynch Syndrome Natalie Taylor TCRN's 2015 Cancer Challenge of the Year - Lynch Syndrome Explainer

Lynch syndrome is a common, inherited condition that affects thousands of Australians and greatly increases the risk of developing cancer. Yet 95% of those who have it don’t know about it. The TCRN funded CCY 2015 aims to support healthcare professionals in developing strategies to improve screening and management...
Lynch syndrome explainer: a common cancer risk

TCRN Member Dr Jason Wong presented at Cancer Institute NSW Big Data, Big Impact from Dr Jason Wong

A team of UNSW medical scientists have discovered that DNA repair is compromised at important regions of our genome, shedding new light on how cancers develop in the human body.
Repairing damage in DNA from anything that causes a mutation, such as UV radiation and tobacco smoke, is a fundamental process that protects our cells from becoming cancerous.

Lead author of the study and TCRN member Dr Jason Wong; group leader of Bioinformatics and Integrative Genomics at the Lowy Cancer Research Centre, said the results provide compelling evidence that increased mutations at gene promoter sites are caused by a compromised nucleotide excision repair ("NER") system.

The study, published in journal Nature, analysed more than 20 million DNA mutations from 1,161 tumours across 14 cancer types. They found that in many cancer types, especially skin cancers, the number of mutations was particular high in regions of the genome known as ‘gene promoters’. Significantly, these DNA sequences control how genes are expressed which in turn determine cell type and function.

The team involved Dilmi Perera, Rebecca Poulos, Anushi Shah, Dominik Beck, John Pimanda and Jason Wong.
Repairing DNA damage in the human body – new insights into how cancers develop

CINSW Grants EOI - Cancer Screening and Prevention Grants 2016 - 2017

The Cancer Institute NSW has announced the Cancer Screening and Prevention Grants 2016-2017.
The grants are offered in five priority areas; Bowel Screening, Breast Screening, Cervical Screening, Primary Care (Bowel, Breast and Cervical Screening) and Tobacco Control.
Read more about the Cancer Institute NSW 2016-2017 grants; EOIs due 10 May 2016

CINSW Innovations Conference 2016 Upcoming Conferences - Abstract Submission

Are you currently working on, or have recently completed, a project designed to improve cancer treatment and care?
The TCRN would like to encourage our members to submit abstracts to this free conference, which provides health professionals with an opportunity to hear, collaborate on and share the latest innovations in quality cancer treatment and care.
Submit your abstract by COB 27 May 2016 for the opportunity to showcase your work!

The theme for this year's Innovations in Cancer Treatment and Care Conference on 9 September 2016 is Psychosocial care, featuring keynote speaker Prof Jane Turner.
Event registration and abstract submission is now open

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